Ophidians are a race of serpent-people who are commonly associated with the yuan-ti. The ophidians are said to be snake-worshiping human cultists who discovered a powerful yuan-ti relic that transformed them into degenerate reptilian humanoids. Ophidians are not very intelligent, and are easily impressed by shows of power by yuan-ti, evil nagas, and dragons, whom they frequently serve as willing slaves. Their most potent weapon is their venom, which can change humans into degenerate ophidians. Most ophidians worship their yuan-ti masters as gods.
They can be found in the jungles of the south or in the ruins of the Underdark.
Ophidians worship the god Sseth.